Crouse Health Online: Wellness is just a click away.
Share Share
  |  Connect with Us: 
large
med
small
Text Size
 

Health News



What Caused 2009 H1N1 Pandemic?

What Caused 2009 H1N1 Pandemic?

08/05/10

THURSDAY, Aug. 5 (HealthDay News) -- The 2009 H1N1 swine flu virus used a new biochemical trick to hijack host cells, a feat that triggered the recent pandemic, according to an international team of scientists.

"We have found why the pandemic H1N1 virus replicated so well in humans," Yoshihiro Kawaoka, a leading influenza expert and a professor of pathobiological sciences at the University of Wisconsin-Madison's School of Veterinary Medicine, said in a university news release.

The H1N1 virus is a combination of four different avian and swine flu viruses that emerged over the past 90 years. It also includes genetic residue of the 1918 pandemic virus that killed as many as 20 million people, Kawaoka explained.

A typical flu virus requires the presence of two amino acids -- lysine and asparagines -- in specific sites on a key avian protein in order to jump from an animal and replicate efficiently in human cells.

But Kawaoka and colleagues found that the lysine amino acid is located in a completely different location on the avian protein in the H1N1 virus. This is what gives the virus the ability to adapt to and co-opt human cells.

The study is published in the Aug. 5 issue of PLoS Pathogens.

"This pandemic H1N1 has this mutation and is why it can replicate so well in humans. This gives us another marker to help predict the possibility of future flu pandemics," Kawaoka said.

As of July 25, 2010, the pandemic virus had caused more than 18,398 deaths worldwide, according to the World Health Organization.

More information

The U.S. Food and Drug Administration has more about the 2009 H1N1 swine flu.

Copyright © 2010 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

OF INTEREST:
 

Latest News

Crouse Employee Lois Wille Walks the Simply Well Lifestyle Talk
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

CrouseSports Express After-Hours Ortho Care

Immediate care of orthopedic injuries in kids and adults.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >