Stent Implantation Linked to Blood Clot Risk in Black
MONDAY, Aug. 30 (HealthDay News) -- Black patients are at
increased risk of developing life-threatening blood clots after
receiving a drug-coated stent to prop open narrowed arteries, U.S.
researchers have found.
The new study included more than 7,200 patients who had stents
coated with clot-prevention drugs implanted between mid-2003 and
the end of 2008.
The researchers found that black patients were nearly three
times more likely to develop a clot compared to patients of other
races. In fact, being black was the strongest predictor that
clotting would occur more than one month after implantation of a
drug-coated stent, the study authors noted.
When the researchers took into account other known risk factors
for clotting -- including diabetes, high blood pressure and kidney
problems -- black patients still had a higher rate of developing a
blood clot, according to the study results.
The clotting rates for blacks compared to non-blacks were:
- 1.71 percent versus 0.59 percent after 30 days.
- 2.25 percent versus 0.79 percent after one year.
- 2.78 percent versus 1.09 percent after two years.
- 3.67 percent versus 1.25 percent after three years.
The findings held true even though black patients took their
prescribed anti-clotting medication at a higher rate than other
races, the study authors pointed out. Possible genetic differences
in the way the patients' bodies react to the anti-clotting
medication may be one potential cause that needs further study, the
researchers suggested in a news release from the American Heart
The study also found that the rate of death from all causes
after three years was almost 25 percent for black patients compared
to about 13 percent for patients of other races.
The higher death rates among black patients are "not just
because this population is sicker or less compliant, but there is
something else there that needs to be explored," lead author Dr.
Ron Waksman, associate director of the cardiology division at
Washington Hospital Center and a professor of medicine and
cardiology at Georgetown University, said in the news release.
The study was released online in advance of publication in an
upcoming print issue of the journal
The U.S. National Heart, Lung, and Blood Institute has more
Copyright © 2010
. All rights reserved.
Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.