Lower Blood Pressure May Help Sicker Kidney
WEDNESDAY, Sept. 1 (HealthDay News) -- Aggressive treatment to
lower high blood pressure may help preserve kidney function and
prevent the need for dialysis in some black patients with chronic
That's the finding of a study published Sept. 2 in the
New England Journal of Medicine.
"This is not a panacea. We have a lot more to figure out. But our evidence suggests that we have a way to at least delay or possibly even prevent end-stage kidney disease in some patients," study leader Dr. Lawrence J. Appel, a professor of medicine at Johns Hopkins University School of Medicine, said in a Hopkins news release.
The study of 1,094 black patients with chronic kidney disease
and high blood pressure found that aggressive treatment to lower
high blood pressure to about 130/80 provided the most benefit to
sicker kidney disease patients -- those with protein in their
In this group of patients, there was about a 25 percent
reduction in end-stage kidney disease compared to those who
achieved a blood pressure goal of 140/90, which is the standard of
doctors when treating patients with high blood pressure.
Among patients who weren't as sick -- those with little or no
protein in their urine -- efforts to lower blood pressure had
little effect on kidney disease progression.
"This has always been a hot topic: Is a lower blood pressure goal better at preserving kidney function than the standard goal? The answer is a qualified yes, notably in people who have some protein in their urine," Appel said.
The findings suggest that doctors should check for protein in
the urine before they determine the blood pressure goal for blacks
with kidney disease, he added.
Blacks account for about one-third of patients with end-stage
kidney disease in the United States, although they make up only 12
percent of the population.
The American Academy of Family Physicians has more about
chronic kidney disease.
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