Low Vitality Score at Birth Associated with Cerebral
FRIDAY, Oct. 8 (HealthDay News) -- A low vitality score at birth
is strongly associated with a later diagnosis of cerebral palsy, a
disorder involving muscle impairment and body movement that appears
during the first few years of life, a new study indicates.
The Apgar score (zero to 10) is based on five vitality-related
criteria -- complexion, pulse rate, reaction when stimulated,
muscle tone, and breathing. An Apgar score of 3 or less is regarded
as critically low, 4 to 6 is fairly low, and 7 to 10 is generally
For this study, researchers examined data from 543,064 Norwegian
children born between 1986 and 1995. Of those children, 988 (1.8 in
1,000) were diagnosed with cerebral palsy before they were 5 years
old. (In Western countries, cerebral palsy generally affects two to
three children out of every 1,000 born.)
The researchers found that children with an Apgar score of less
than 3 at birth had a 100-fold higher incidence of cerebral palsy
than those with a score of 10. The association between a low Apgar
score and cerebral palsy was high in children with normal birth
weight and modest in children with low birth weight.
"Despite the strong association of low Apgar score with cerebral palsy, it is encouraging that almost 90 percent of children with an Apgar score of less than 4 did not develop cerebral palsy," the researchers wrote.
They said their findings suggest that the causes of cerebral
palsy are closely associated with factors that reduce infant
vitality, they concluded. They suggested that a low Apgar score may
sometimes indicate brain impairment that occurred during pregnancy
In an accompanying editorial, professor Nigel Paneth of Michigan
State University said that although most babies with a low Apgar
score recover and do well, infants with a low score "should be
watched closely for the persistence or development of brain damage,
especially in the light of robust evidence that babies with brain
injury may benefit from head or body cooling."
The study is published Oct. 8 in
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