Low Testosterone May Raise Risk of Early Death:
TUESDAY, Oct. 19 (HealthDay News) -- Men with low testosterone
levels may be at increased risk for premature death from heart
disease and all causes, a finding that challenges the current
belief that testosterone is a risk factor for cardiovascular
disease, according to new research.
The study included 930 men with coronary artery disease who were
followed-up for about seven years. At the start of the study, low
testosterone levels were noted in about one-quarter of the men.
During the study period, one in five men (20 percent) with low
testosterone levels died, compared with one in eight (12 percent)
of those with normal levels of the hormone, according to the report
in the Oct. 20 online edition of the journal
After taking into account other risk factors -- such as age,
co-existing health problems, smoking and weight -- a low
testosterone level was found to be an independent risk factor for
premature death from heart disease and all other causes, reported
Kevin Channer, of the department of cardiology at Royal Hallamshire
Hospital Sheffield, in the United Kingdom, and colleagues.
Borderline levels of testosterone were also associated with
increased risk of death, the study authors found.
Low, rather than high, levels of testosterone are associated
with obesity, risky blood fats and insulin resistance, all of which
are risk factors for diabetes and heart disease, the researchers
noted in a news release from the journal's publisher. They
suggested that men at high risk for these diseases might have the
most to gain from testosterone replacement therapy.
The American Association for Clinical Chemistry has more about
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