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Pradaxa Approved for Atrial Fibrillation

Pradaxa Approved for Atrial Fibrillation

10/20/10

WEDNESDAY, Oct. 20 (HealthDay News) -- Pradaxa (dabigatran etexilate) has been approved by the U.S. Food and Drug Administration to help prevent stroke in people with a type of abnormal heart rhythm called atrial fibrillation.

The condition, which occurs when the heart's two upper chambers beat quickly and out of sync, affects more than 2 million Americans, the agency said in a news release.

Pradaxa is an anti-clotting drug that inhibits an enzyme involved in blood clotting. Clinical studies of the drug found that when compared with the popular anticoagulant warfarin, people with atrial fibrillation had fewer strokes on Pradaxa than those on warfarin, the FDA said.

As with other anti-clotting drugs, a potential side effect is life-threatening bleeding, the agency said. Other potential adverse reactions include stomach discomfort or pain, nausea, heartburn and bloating.

Pradaxa is produced in 75 milligram and 150 milligram strengths by Boehringer Ingelheim Pharmaceuticals, based in Ridgefield, Conn.

More information

The American Heart Association has more about atrial fibrillation.

Copyright © 2010 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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