Asthma Linked to Lung Cancer Risk in Study11/03/10
WEDNESDAY, Nov. 3 (HealthDay News) -- University of Missouri
researchers believe they have found a correlation between asthma
and lung cancer in a small study.
Previous research has shown a correlation between chronic
obstructive pulmonary disease (COPD) and lung cancer, but this is
the first time such a link has been shown for asthma and lung
cancer, the researchers said.
However, based on the available data, people with asthma should
not worry that they are at an increased risk for developing lung
cancer, said Dr. Marilyn Glassberg, an associate professor of
clinical medicine, pulmonary and critical care medicine at the
University of Miami Miller School of Medicine.
"This is a correlation study," she said. "The problem with correlation studies is you never get cause-and-effect." Still, "it's of interest," she added.
The findings were to be presented Tuesday by lead researcher Dr.
Vamsi Guntur at the annual meeting of the American College of Chest
Physicians in Vancouver.
For the study, Guntur's team examined the medical records of 759
lung cancer patients and similar patients without lung cancer.
The researchers found that 46.2 percent of those with asthma
also had lung cancer, compared with 22.5 percent of those without
The researchers speculate that "chronic repeated inflammatory
insults from asthma" could trigger lung cancer, but exactly how
that might happen remains unclear, they said in a news release from
The authors say their study "underscores the importance of more
aggressive management of inflammatory airway disease, development
of diagnostics for early and ideally noninvasive screening and risk
stratification, and promotion of additional research on the
mechanisms of carcinogenesis induced by inflammation."
Glassberg took issue with the findings, noting that while asthma
and COPD scar the lungs, lung cancer is not caused by scarring of
lung tissue. Also, she said it doesn't appear that the researchers
took into account smoking, which is a major cause of lung
"This is not going to change how we take care of people, or [cause us] to screen asthmatics for lung cancer," she said.
For more information on asthma, visit the
U.S. National Library of Medicine.
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