Study Sees Link Between Low Salt Levels, Fracture Risk in
SATURDAY, Nov. 20 (HealthDay News) -- New research links
lower-than-normal levels of sodium (salt) in the blood to a higher
risk of broken bones and falls in older adults.
Even mildly decreased levels of sodium can cause problems, the
"Screening for a low sodium concentration in the blood, and treating it when present, may be a new strategy to prevent fractures," study co-author Dr. Ewout J. Hoorn, of Erasmus Medical Center in Rotterdam, the Netherlands, said in a news release from the American Society of Nephrology.
There's still a mystery: There doesn't appear to be a link
between osteoporosis and low sodium levels, known as hyponatremia,
so it's not clear why lower sodium levels may lead to more
fractures and falls, the study authors said.
The researchers examined the medical records for six years of
more than 5,200 Dutch people over the age of 55. The study authors
wanted to confirm findings in recent research that linked low
sodium to falls, broken bones and osteoporosis, Hoorn said.
About 8 percent of the participants had low sodium levels, which
often develop when the kidneys hold too much water. The 8 percent
were also more likely to have diabetes and use diuretics (water
About a quarter of the people with low sodium levels had falls,
compared to 16 percent of the others in the study, and their risk
of vertebral/vertebral compression fractures was 61 percent higher.
The risk of non-spinal fractures, such as broken hips, was 39
Those with low sodium were also 21 percent more likely to die
during the six-year period.
"Although the complications of hyponatremia are well-recognized in hospitalized patients, this is one of the first studies to show that mild hyponatremia also has important complications in the general population," Hoorn said.
More research is needed to clarify the apparent link between low
sodium levels and increased fracture risk. In the interim,
"Screening older adults for and treatment of hyponatremia may be an
important new strategy to prevent fractures," Hoorn said.
The study findings were to be presented Friday at the American
Society of Nephrology's annual meeting, in Denver.
While the study found an association between low salt levels and
risk of fractures, it did not prove a cause-and-effect. And
research presented at medical meetings should be considered
preliminary until published in a peer-reviewed journal.
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