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Axiron Approved as First Underarm Testosterone Drug

Axiron Approved as First Underarm Testosterone Drug


WEDNESDAY, Nov. 24 (HealthDay News) -- Axiron has been approved by the U.S. Food and Drug Administration as the first topical testosterone solution to be applied to the underarm, makers Eli Lilly and Acrux said in a news release.

Previously approved forms of testosterone replacement therapy have included tablets, skin patches, injections and topical gels. As many as 13 million men aged 45 or older in the United States have symptoms of low testosterone, including decreased sexual desire, fatigue, depressed mood and osteoporosis, the companies said.

Adverse reactions reported during clinical testing of Axiron included skin reactions, increased red blood cell count, headache, diarrhea, vomiting and an increase in blood levels of Prostate Specific Antigen, a screening marker for prostate cancer.

Axiron hasn't been studied in males younger than 18, the drug makers said.

The hormone can be transferred to others via close contact. Unexpected signs of puberty have been reported among young children accidentally exposed to testosterone. Axiom users should immediately cover the applied area and wash their hands to help avoid this possibility, the companies said.

More information

To learn more about testosterone replacement therapy, visit the U.S. National Institute on Aging.

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Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.


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