Crouse Health Online: Wellness is just a click away.
Share Share
  |  Connect with Us: 
large
med
small
Text Size
 

Health News



Rash Due to Lung Cancer Drug May Be Linked to Better Survival

Rash Due to Lung Cancer Drug May Be Linked to Better Survival

12/20/10

MONDAY, Dec. 20 (HealthDay News) -- Lung cancer patients who develop a rash after treatment with the drug cetuximab (Erbitux) have better outcomes, according to a new study.

German researchers compared hundreds of patients with non-small cell lung cancer who received chemotherapy plus cetuximab and hundreds of patients who received chemotherapy alone. About 70 percent of the patients who received the combination therapy developed an acne-like rash within the first three weeks of treatment.

Compared to other patients, those who developed the rash lived longer (15 months vs. 8.8 months), had better progression-free survival (5.4 months vs. 4.3 months) and had a higher response rate (44.8 percent vs. 32 percent), according to the report by Dr. Ulrich Gatzemeier, from Hospital Grosshansdorf in Germany, and colleagues.

The findings, published online Dec. 19 in The Lancet Oncology, suggest that the early appearance of a skin rash may help identify patients who would be most likely to respond to treatment with cetuximab and gain the greatest survival benefit, the researchers noted.

The study authors concluded that further clinical trials are needed "to verify this finding and assess it fully in the context of possible clinical application."

In a commentary accompanying the report, Dr. Francesco Perrone from the Istituto Nazionale Tumori in Naples, Italy, added: "The only way to verify the hypothesis that skin rash predicts the benefit of cetuximab is a randomized trial that compares interruption versus continuation of cetuximab in patients with skin rash after three weeks of treatment with cetuximab and chemotherapy."

The findings, Perrone continued, "must be validated prospectively before we consider the introduction of cetuximab into clinical practice for the treatment of patients with advanced non-small cell lung cancer."

More information

The American Cancer Society has more about non-small cell lung cancer.

Copyright © 2010 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

OF INTEREST:
 

Latest News

Crouse Hospital Appoints Chief Information Officer
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >