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Genome Map of Multiple Myeloma Offers Clues to Its Cause

Genome Map of Multiple Myeloma Offers Clues to Its Cause

03/23/11

WEDNESDAY, March 23 (HealthDay News) -- The genome of the highly aggressive blood cancer multiple myeloma has been mapped by a team of North American scientists, who say their achievement will improve understanding of what causes the disease and may lead to new treatments.

"For the first time, we are able to see on a molecular basis what might be causing this malignancy," Dr. David S. Siegel, chief of the multiple myeloma division at the John Theurer Cancer Center at Hackensack University Medical Center in New Jersey, said in a news release from the center.

"We already know what causes many types of cancer, but until now, we had few clues to the causes of myeloma," he added.

He and colleagues from 20 major research institutions examined genomes of both tumor and normal blood cells in 38 people with multiple myeloma.

"We have developed the most comprehensive molecular picture of myeloma to date, which will provide a public resource of genomic information for this disease," Siegel said. "This is a large step forward in personalized medicine for the treatment of multiple myeloma. My hope is that this will allow us to develop more targeted, effective therapies."

Their findings are reported in the March 24 issue of Nature.

More information

The American Cancer Society has more about multiple myeloma.

Copyright © 2011 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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