Crouse Health Online: Wellness is just a click away.
Share Share
  |  Connect with Us: 
large
med
small
Text Size
 

Health News



Blood Pressure Drug Helps Those With Mild Heart Failure

Blood Pressure Drug Helps Those With Mild Heart Failure

05/23/11

SUNDAY, May 22 (HealthDay News) -- New Swedish research suggests that the drug Inspra reduces the threat of major cardiovascular complications among patients who have a mild form of heart failure.

This latest finding builds on earlier work that was published by the New England Journal of Medicine last fall. That study suggested that Inspra (eplerenone), an aldosterone antagonist, helps control cardiovascular complications among patients with a history of serious chronic heart failure.

Since far more people suffer from mild heart failure, this new finding could mean the drug might benefit a far broader group of patients, the researchers added.

The Swedish analysis makes an even stronger case for the use of Inspra in patients with mild heart failure because, in addition to reducing mortality, it also reduces the incidence of the irregular heart beat condition known as atrial fibrillation, study co-author Karl Swedberg, from the University of Gothenburg in Sweden, said in a news release from the European Society of Cardiology.

Atrial fibrillation "is a condition which both increases morbidity and complicates the care of patients with heart failure," he explained.

Swedberg and his colleagues were slated to present the findings Sunday in Gothenburg at the Heart Failure Congress 2011, organized by the Heart Failure Association of the European Society of Cardiology.

The study team noted that Inspra is currently approved for the control of high blood pressure as well as for the treatment of heart attack patients who experience congestive heart failure. It is not yet approved for the treatment of patients who experience mild heart failure. It is available generically in the United States, according to the news release.

Experts estimate that almost 6 million people in the United States suffer from heart failure.

The current finding stems from a re-analysis of a larger study that involved more than 2,700 heart failure patients being cared for at 278 different health centers.

Focusing specifically on those participants who had experienced mild (class 2) heart failure, the authors found that just 2.7 percent of those patients who were placed on a regimen of between 25 milligrams to 50 milligrams daily of Inspra for a little less than two years experienced atrial fibrillation.

This compared with 4.5 percent of those patients who were randomized to receive a sugar pill instead.

Dr. Byron K. Lee, director of the Electrophysiology Laboratories and Clinics within the division of cardiology at the University of California, San Francisco, noted that exactly how Inspra seems to help heart patients is not well understood.

"It is unclear how eplerenone works to lower the risk of abnormal heart rhythms like atrial fibrillation and atrial flutter," he said. "However, there are many potential mechanisms. One possibility is that eplerenone may help maintain potassium levels. Patients with heart failure are often on high-dose diuretics that remove fluid at the expense of removing potassium. Thats why heart failure patients need to watch their potassium level vigilantly."

More information

For more on atrial fibrillation, go to National Library of Medicine.

Copyright © 2011 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

OF INTEREST:
 

Latest News

Crouse Hospital Appoints Chief Information Officer
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >