Scientists Zero In on Key Melanoma Links06/21/11
TUESDAY, June 21 (HealthDay News) -- Researchers say they've
pinpointed a small number of genetic variants that are most
strongly linked with the risk of melanoma, the most dangerous form
of skin cancer.
The international team analyzed the findings of more than 100
previously published studies and found that just five variants are
significantly associated with melanoma at the genome-wide level and
strongly backed by population-wide studies.
The study appears online June 21 in the
Journal of the National Cancer Institute.
The gene variants are on chromosomes that play an important role
in determining a person's skin, hair and eye color.
However, the authors said in a journal news release that the
findings should be considered with caution, noting that the genetic
areas under study were chosen "because of their effect on
pigmentation, which is known to be associated with melanoma
About 68,000 U.S. adults were expected to be diagnosed with
melanoma in 2010, according to the U.S. National Cancer
The American Academy of Family Physicians has more about
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