Blacks at Higher Risk for Resistant Breast Cancer:
TUESDAY, Aug. 16 (HealthDay News) -- Black women are more likely
to have two or more children and are less likely to breast-feed,
putting them at greater risk of developing a difficult-to-treat
type of breast cancer, according to a new study.
The study, published in the current issue of
Cancer Epidemiology, Biomarkers & Prevention, found the risk for hormone receptor-negative breast cancer was 50 percent greater among women who gave birth to at least two children. The researchers noted, however, that breast-feeding reduced that risk.
"African American women are more likely to have had a greater number of full-term births and less likely to have breast-fed their babies," Julie Palmer, professor of epidemiology at the Slone Epidemiology Center at Boston University, said in a news release from the American Association for Cancer Research. "This study shows a clear link between that and hormone receptor-negative breast cancer."
The research was based on the Black Women's Health Study, which
has followed 59,000 African American women since 1995. The study
authors analyzed medical information on 457 of the women with
hormone receptor-positive breast cancer as well as 318 women who
developed hormone receptor-negative breast cancer.
In contrast, higher birth rates decreased the women's risk for
estrogen receptor-positive breast cancer, the study found. For
those women, researchers found no link between breast-feeding and
their risk for the disease.
"The adverse effect of high childbirth without subsequent breast-feeding seems to be confined to the hormone receptor-negative breast cancer, which carries a higher mortality rate and is more common in African Americans," concluded Palmer.
The U.S. National Cancer Institute provides more information on
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