Crouse Health Online: Wellness is just a click away.
Share Share
  |  Connect with Us: 
large
med
small
Text Size
 

Health News



U.S. Scientists Map Genome of Advanced Prostate Cancer

U.S. Scientists Map Genome of Advanced Prostate Cancer

09/27/11

TUESDAY, Sept. 27 (HealthDay News) -- A number of recurrent genetic errors common to advanced lethal prostate cancers have been identified by scientists who conducted the first complete genome mapping of these types of cancers.

The team also identified several instances of genetic "hypermutation," an excess of single-letter DNA errors that can give the cancers resistance to therapies commonly used to slow advanced prostate cancer, such as surgical castration and androgen-blocking drugs.

The study by researchers at the Fred Hutchinson Cancer Research Center and the University of Washington in Seattle was published in this week's online edition of the Proceedings of the National Academy of Sciences.

"The most interesting finding to come out of our DNA sequencing project was the discovery of three aggressive tumor types that had 10 times the number of mutations compared to the other advanced prostate cancers we studied," co-corresponding author Dr. Peter S. Nelson said in a research center news release.

"That was very surprising and unusual. We don't know the cause of these hypermutated tumors, but the frequency of the mutations suggests these tumors might evolve very rapidly to develop resistance to therapies," he added.

The discovery of these genetic mutations could help improve understanding of why some prostate cancers are so deadly, and could also lead to improved screening tests or treatments, Nelson suggested.

More information

The American Cancer Society has more about prostate cancer.

Copyright © 2011 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

OF INTEREST:
 

Latest News

Crouse Hospital Appoints Chief Information Officer
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >