Crouse Health Online: Wellness is just a click away.
Share Share
  |  Connect with Us: 
large
med
small
Text Size
 

Health News



MRI Scans Show Brain Changes in Kids With Schizophrenia

MRI Scans Show Brain Changes in Kids With Schizophrenia

01/04/12

WEDNESDAY, Jan. 4 (HealthDay News) -- Children who are diagnosed with schizophrenia or a number of other psychoses go on to experience a progressively greater than normal loss of gray matter in the frontal lobe region of the brain, new research suggests.

These adolescents also experience an above-average spike in the amount of so-called "cerebrospinal fluid" found in the same location, according to a report published in the January issue of the Archives of General Psychiatry.

In turn, children who experience these brain developments appear to face an increased risk for longer hospitalization, more severe illness and a poorer overall prognosis, the authors of the study noted.

"We found progression of gray matter volume loss after a two-year follow-up in patients who ended up with a diagnosis of schizophrenia, but not bipolar disease, compared with healthy controls," Dr. Celso Arango, of the Hospital General Universitario Gregorio Maranon in Madrid, Spain, and colleagues said in a journal news release.

"Some of these pathophysiologic processes seem to be markers of poorer prognosis," the researchers added.

The findings stem from an analysis of brain changes detected using MRI scans taken over a two-year period among 61 patients who had been diagnosed with a range of different psychoses at one of six child and adolescent psychiatric facilities in Spain.

In all, brain changes among 25 children diagnosed with schizophrenia, 16 with bipolar disorder and 20 with a number of other psychoses were stacked up against the brain status of 70 healthy children.

The result: in addition to the principal findings, the team further observed that total brain gray matter (as well as gray matter in the left parietal region of the brain) were notably different among patients with schizophrenia compared with their healthy peers.

"To develop therapeutic strategies to counteract these pathologic progressive brain changes, future studies should focus on their neurobiological underpinnings," the study authors advised.

More information

For more on adolescent schizophrenia, visit the American Academy of Child and Adolescent Psychiatry.

Copyright © 2012 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

OF INTEREST:
 

Latest News

Crouse Hospital Appoints Chief Information Officer
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >