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Elelyso Approved for Gaucher Disease

Elelyso Approved for Gaucher Disease

05/01/12

TUESDAY, May 1 (HealthDay News) -- Elelyso (taliglucerase alfa) has been approved by the U.S. Food and Drug Administration as a long-term enzyme replacement therapy for people with a rare genetic disorder called type 1 Gaucher disease.

People with the disorder don't produce enough of an enzyme called glucocerebrosidase. This causes the buildup of fatty lipids in the spleen, liver, kidneys and other organs. Warning signs of the disorder may include anemia, low blood platelets and bone problems, the FDA said in a news release. About 6,000 people in the United States are thought to have the disorder.

Elelyso, an every-other-week professionally administered injection, was clinically evaluated in a study of 56 people with type 1 Gaucher disease. The most common side effects included allergic reactions, headache, chest pain, fatigue, increased blood pressure, back or joint pain, and flushing.

Elelyso is produced and distributed by New York City-based Pfizer, under license from Protalix BioTherapeutics.

More information

Medline Plus has more about Gaucher disease.

Copyright © 2012 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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