Scans Spot Brain Changes in Patients With Concussion Syndrome11/21/12
WEDNESDAY, Nov. 21 (HealthDay News) -- Researchers who
identified brain changes in people with post-concussion syndrome
say their findings may lead to improved detection and treatment of
Symptoms of post-concussion syndrome, which occurs in 20 percent
to 30 percent of people who suffer mild traumatic brain injury,
include headache and memory and concentration problems.
In this study, published online Nov. 21 in the journal
Radiology, researchers conducted MRI brain scans of 18
healthy people and 23 people who had symptoms of post-concussion
syndrome two months after suffering a mild-traumatic brain
The MRI scans were done when the participants' brains were in a
resting state, such as when the mind wanders or while daydreaming.
It is believed that the resting state involves connections among a
number of brain regions and that the default-mode network plays a
major role, study author Dr. Yulin Ge, an associate professor in
the radiology department at the NYU School of Medicine in New York
City, said in a journal news release.
Previous research has shown that the default-mode network is
altered in people with brain disorders such as Alzheimer's disease,
autism and schizophrenia.
This study found that communications and information integration
in the brains of the people with post-concussion syndrome were
disrupted among key default-mode network structures, and that the
brain had to tap into different areas to compensate for this
Through their ongoing research, Ge and colleagues hope to
identify a biological feature, or biomarker, that can be used to
monitor post-concussion syndrome progression and recovery, and to
assess the effects of treatment.
The U.S. Centers for Disease Control and Prevention offers
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