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Dementia, Late-Life Depression May Be Linked

Dementia, Late-Life Depression May Be Linked

01/04/13

FRIDAY, Jan. 4 (HealthDay News) -- Older people with depression may be more likely to experience mild mental impairment or dementia than their peers, Dutch researchers report.

In a study of nearly 2,200 Medicare recipients aged 65 and older, researchers led by Dr. Edo Richard of the University of Amsterdam examined the association between late-life depression and dementia and thinking/memory difficulties known as mild cognitive impairment (MCI).

The study, published online Dec. 31 in the journal Archives of Neurology, found that people with depression were 40 percent more likely to have mild mental impairment and more than twice as likely to have full-blown dementia. Although depression also was linked to greater risk for incident dementia, it was not associated with incident problems with thinking and memory.

The study authors said those with both mild cognitive impairment and depression were at increased risk for developing dementia, particularly vascular dementia. They noted, however, that these patients were not at greater risk for Alzheimer's disease, the most common form of dementia.

"Our finding ... suggests that depression develops with the transition from normal cognition to dementia," the authors wrote in a journal news release.

Depression affects between 3 percent and 63 percent of people with mild cognitive impairment. Previous studies have found that those with a history of depression are at greater risk for dementia. The researchers added that there is no clear explanation for the link between late-life depression and cognitive impairment, and their study does not establish a direct cause-and-effect relationship.

More information

The U.S. National Institute of Mental Health provides more information on depression.

Copyright © 2013 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

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