Weight-Loss Surgery May Affect Fat-Related Genes04/11/13
THURSDAY, April 11 (HealthDay News) -- Weight-loss surgery
changes the levels of genes involved in burning and storing fat, a
new study says.
The findings may help lead to the development of new drugs that
mimic this weight-loss-associated control of gene regulation, said
the authors of the study published online April 11 in the journal
"We provide evidence that in severely obese people, the levels of specific genes that control how fat is burned and stored in the body are changed to reflect poor metabolic health," senior author Juleen Zierath, a professor with the Karolinska Institute in Sweden, said in a journal news release.
"After [weight-loss] surgery, the levels of these genes are restored to a healthy state, which mirrors weight loss and coincides with overall improvement in metabolism," Zierath explained.
Weight-loss surgery -- also called bariatric surgery -- can help
obese people lose large amounts of weight in a short time. The
surgery also leads to early remission of type 2 diabetes in many
The U.S. National Institute of Diabetes and Digestive and Kidney
Diseases has more about
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