Scientists Discover More Genetic Clues to Testicular Cancer05/13/13
SUNDAY, May 12 (HealthDay News) -- Twelve new genetic regions
associated with an increased risk of testicular cancer have been
identified by researchers in two studies.
One study identified four regions and the other identified eight
regions, bringing to 17 the total number of genetic regions
associated with testicular cancer. The studies were published
online May 12 in the journal
Testicular cancer is the most common type of cancer diagnosed in
young American men.
The findings could eventually help scientists better understand
which men are at high risk and enable early detection or possibly
even prevention of the disease, the researchers said.
The team, including Peter Kanetsky, an associate professor of
biostatistics and epidemiology at the University of Pennsylvania
Perelman School of Medicine, identified four of the 12 new genetic
regions after analyzing the genomes of more than 13,000 men.
None of the four regions has been linked to other cancers. They
pose a higher risk than other regions identified for some common
cancers, such as breast and prostate cancer, according to a school
Testicular cancer is highly inheritable. A man whose father or
son has testicular cancer has a four to six times higher risk of
developing the disease than a man with no family history. The risk
is up to 10 times higher if the man also has a brother with
The American Cancer Society has more about
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