Radiation Before Surgery May Improve Survival From Rare Lung Cancer01/23/14
THURSDAY, Jan. 23, 2014 (HealthDay News) -- Patients with a rare
type of lung cancer might be more likely to survive if they have
radiation therapy before -- rather than after -- surgery, according
to a small new study.
The study included 25 patients with mesothelioma who underwent
five days of radiation therapy and had surgery to remove the
affected lung the following week. Many patients who develop
mesothelioma have been exposed to asbestos, the researchers
"The patients in our study experienced shorter treatment, fewer complications and speedier recovery," study lead author Dr. John Cho, a radiation oncologist at Princess Margaret Cancer Center in Toronto, said in a University Health Network news release. "The three-year survival rate more than doubled to 72 percent from 32 percent."
The findings about this treatment method -- called Surgery for
Mesothelioma After Radiation Therapy (SMART) -- were published
online Jan. 20 in the
Journal of Thoracic Oncology.
Dr. Marc de Perrot, an associate professor of surgery at the
University of Toronto and head of the Toronto Mesothelioma Research
Program, also weighed in on the study's findings.
>"It was imperative to do the surgery quickly because the
lung is particularly sensitive to radiation toxicity," said de
Perrot, the study's co-author.
The SMART approach cut the treatment cycle for patients to one
month from five months, de Perrot said. It also reduced the risk of
recurrence because the radiation wiped out the cancer's ability to
seed itself elsewhere in the chest or abdomen during surgery, he
"These research results offer real hope to mesothelioma patients who have too often been told in the past that they may have only six months to live," de Perrot said.
Since completing the study, Cho and de Perrot have used the
approach to successfully treat 20 more patients, according to the
The American Lung Association has more about
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