Crouse Health Online: Wellness is just a click away.
Share Share
  |  Connect with Us: 
large
med
small
Text Size
 

Health News



Scientists ID New Genes Linked to Belly Fat

Scientists ID New Genes Linked to Belly Fat

01/23/14

THURSDAY, Jan. 23, 2014 (HealthDay News) -- Researchers who identified five new genes linked to belly fat say their findings could help efforts to develop medicines to treat obesity or obesity-related diseases such as heart disease, diabetes and cancer.

The investigators looked at more than 57,000 people of European descent and searched for genes associated with abdominal fat, independent of overall obesity. They examined more than 50,000 variants in 2,000 genes.

The team pinpointed three new genes associated with increased waist-to-hip ratio in both women and men, and identified two other genes that appear to affect waist-to-hip ratio in women only. Waist-to-hip ratio is used to measure a person's belly fat. It's believed that genetics account for 30 percent to 60 percent of waist-to-hip ratio.

Abdominal fat is a predictor of obesity-related disease, according to the U.S. Centers for Disease Control and Prevention.

The new study found that of the two genes that only seem to affect women, one called SHC1 appears to interact with 17 other proteins known to play a role in obesity. SHC1 has been found to be highly active in fat tissue.

"This is the first time SHC1 has been associated with abdominal fat," study author Kira Taylor, an assistant professor at the University of Louisville School of Public Health and Information Sciences, said in a university news release.

"We believe this discovery holds great opportunity for medicinal chemistry and eventually, personalized medicine," Taylor said. "If scientists can find a way to fine-tune the [activity] of this gene, we could potentially reduce the risk of excessive fat in the mid-section and its consequences, such as cardiovascular disease."

The study was recently published online in the journal Human Molecular Genetics.

Previous research has found that mice without the SHC1 protein are leaner than those with the protein, the news release noted.

More information

The U.S. National Heart, Lung, and Blood Institute has more about overweight and obesity.

Copyright © 2014 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.

OF INTEREST:
 

Latest News

Crouse Hospital Appoints Chief Information Officer
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

CrouseSports Express After-Hours Ortho Care

Immediate care of orthopedic injuries in kids and adults.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >