Crouse Health Online: Wellness is just a click away.
  |  Connect with Us: 
Text Size

Health News

Tamiflu Saved Lives During Swine Flu Pandemic, Study Confirms

Tamiflu Saved Lives During Swine Flu Pandemic, Study Confirms


TUESDAY, March 18, 2014 (HealthDay News) -- The antiviral drug Tamiflu reduced the risk of death by 25 percent among adults hospitalized during the 2009 H1N1 swine flu pandemic, according to a new review.

Also, antiviral treatment within 48 hours of developing flu symptoms halved the risk of death compared with starting treatment later or receiving no treatment, according to the study, which was published March 18 in the journal The Lancet Respiratory Medicine.

The risk of death rose by about 20 percent for every 24 hours that treatment was delayed after 48 hours since the start of symptoms, the researchers also found.

"As expected, early treatment seems to be optimal, and treatment shouldn't be delayed by even one day to wait for diagnostic test results," Alicia Fry, of the U.S. Centers for Disease Control and Prevention, wrote in an accompanying journal editorial. "However, if the patient presents for care more than two days after illness onset, treatment might still have some benefit, especially if they are severely ill."

Although treatment with Tamiflu (oseltamivir) reduced the risk of death in many groups of adults -- including pregnant women and severely ill patients -- it didn't significantly reduce death risk among children.

The researchers analyzed data from 78 studies that included more than 29,000 patients of all ages in 38 countries who were hospitalized with confirmed or suspected H1N1 infection between Jan. 2, 2009, and March 14, 2011.

Study lead author Professor Jonathan Nguyen-Van-Tam, of the University of Nottingham, in England, said many governments have stockpiles of Tamiflu approaching its expiration date. "But until now," Nguyen-Van-Tam said, "they had no adequate data to assist them in deciding if lives were saved in 2009 and 2010 or not, and whether they should replenish or not."

"The situation is made more complex by the fact that when an influenza pandemic occurs, even with the best will in the world, vaccine arrives six months too late and its public-health benefit is therefore moderate at best," he said. "Thus we are left with antivirals like Tamiflu and public-health measures like handwashing and social distancing as the only defenses we have for the first six months of a pandemic."

Even though the review found that Tamiflu did not appear to reduce children's risk of death, Fry said the potential benefit of treatment with the drug "for severely ill children is substantial and outweighs any potential risk associated with treatment."

More information

The U.S. National Institutes of Health has more about H1N1 flu.

Copyright © 2014 HealthDay. All rights reserved.

Please be aware that this information is provided to supplement the care provided by your physician. It is neither intended nor implied to be a substitute for professional medical advice. CALL YOUR HEALTHCARE PROVIDER IMMEDIATELY IF YOU THINK YOU MAY HAVE A MEDICAL EMERGENCY. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition.


Latest News

CNY Brain Aneurysm Awareness Campaign Raises Funds for Crouse Neuroscience Institute
more >

MedEx Bedside Prescription Delivery Service

Free service offers convenience, patient education at discharge.
more >

Weight Loss Surgery

Is it right for you? Attend a free information seminar held twice monthly.
more >

Quality at Crouse

See how Crouse Hospital strives to provide the best in patient care.
more >

Cheer Up That Special Someone

Say get well or welcome a new arrival with a gift purchased right at Crouse.

more >

Make an Online Donation Now

Your donation of any amount helps support Crouse services & programs in a meaningful way.
more >

Shop Online Now

Say get well, thinking of you or welcome new baby with a unique gift from the Crouse Gift Shop.

more >